Sophie THEIS PostDoc in Tim Saunders' lab

Publications

Highlighted

CellMet: Extracting 3D shape and topology metrics from confluent cells within tissues
CellMet: Extracting 3D shape and topology metrics from confluent cells within tissues
Sophie Theis, Mario A. Mendieta-Serrano, Bernardo Chapa-y-Lazo, Juliet Chen, Timothy E. Saunders
PLOS Computational Biology  ·  30 Jul 2025  ·  doi:10.1371/journal.pcbi.1013260

Preprint

Identification of optimal fluorophores for use in the Drosophila embryo
Bernardo Chapa-y-Lazo, Thamarailingam Athilingam, Prabhat Tiwari, Prachi Pathak, Shaobo Zhang, Sophie Theis, Timothy E. Saunders
BioRxiv  ·  30 Sep 2025  ·  https://doi.org/10.1101/2025.09.29.678560
A structural transition ensures robust formation of skeletal muscle
Mario A. Mendieta-Serrano, Yiqi Hou, Sophie Theis, Thomas E. Hall, Shannon E. Taylor, Berta Verd, Robert G. Parton, Timothy E. Saunders
BioRxiv  ·  22 Sep 2025  ·  https://doi.org/10.1101/2025.09.22.677369
Boundary constraints can determine pattern emergence
Yi Ting Loo, Juliet Chen, Ryan Harrison, Tiago Rito, Sophie Theis, Guillaume Charras, James Briscoe, Timothy E. Saunders
BioRxiv  ·  22 Jul 2025  ·  doi:10.1101/2025.07.21.665949
Stress anisotropy in 3D active curved structures
Yuting Lou, Sophie Theis, Jean-Francois Rupprecht, Timothy E. Saunders, Tetsuya Hiraiwa
BioRxiv  ·  18 Apr 2025  ·  doi:10.1101/2025.04.13.648577

All

2025

CellMet: Extracting 3D shape and topology metrics from confluent cells within tissues
CellMet: Extracting 3D shape and topology metrics from confluent cells within tissues
Sophie Theis, Mario A. Mendieta-Serrano, Bernardo Chapa-y-Lazo, Juliet Chen, Timothy E. Saunders
PLOS Computational Biology  ·  30 Jul 2025  ·  doi:10.1371/journal.pcbi.1013260

2023

DISSECT is a tool to segment and explore cell and tissue mechanics in highly deformed 3D epithelia
DISSECT is a tool to segment and explore cell and tissue mechanics in highly deformed 3D epithelia
Tatiana Merle, Sophie Theis, Alain Kamgoué, Emmanuel Martin, Florian Sarron, Guillaume Gay, Emmanuel Farge, Magali Suzanne
Developmental Cell  ·  01 Oct 2023  ·  doi:10.1016/j.devcel.2023.07.017
Curvature-Induced Cell Rearrangements in Biological Tissues
Curvature-Induced Cell Rearrangements in Biological Tissues
Yuting Lou, Jean-Francois Rupprecht, Sophie Theis, Tetsuya Hiraiwa, Timothy E. Saunders
Physical Review Letters  ·  06 Mar 2023  ·  doi:10.1103/PhysRevLett.130.108401

2022

Force-generating apoptotic cells orchestrate avian neural tube bending
Force-generating apoptotic cells orchestrate avian neural tube bending
Daniela Roellig, Sophie Theis, Amsha Proag, Guillaume Allio, Bertrand Bénazéraf, Jérôme Gros, Magali Suzanne
Developmental Cell  ·  01 Mar 2022  ·  doi:10.1016/j.devcel.2022.02.020

2021

Tyssue: an epithelium simulation library
Tyssue: an epithelium simulation library
Sophie Theis, Magali Suzanne, Guillaume Gay
Journal of Open Source Software  ·  07 Jun 2021  ·  doi:10.21105/joss.02973
Arp2 3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment
Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment
Emmanuel Martin, Sophie Theis, Guillaume Gay, Bruno Monier, Christian Rouvière, Magali Suzanne
Developmental Cell  ·  01 Mar 2021  ·  doi:10.1016/j.devcel.2021.01.005

2019

Mechanical impact of epithelial mesenchymal transition on epithelial morphogenesis in Drosophila
Mechanical impact of epithelial−mesenchymal transition on epithelial morphogenesis in Drosophila
Mélanie Gracia, Sophie Theis, Amsha Proag, Guillaume Gay, Corinne Benassayag, Magali Suzanne
Nature Communications  ·  04 Jul 2019  ·  doi:10.1038/s41467-019-10720-0